IGF-1 LR3 is an 83-amino-acid analog of insulin-like growth factor 1 with an arginine substitution and a 13-amino-acid N-terminal extension.
Mechanism of Action:
Reduced affinity for IGF binding proteins leaves more of the analog free to engage the IGF-1 receptor, extending its activity in vitro.
Research Applications:
- IGF-1 receptor signaling
- Cell culture and proliferation assays
- Comparison with native IGF-1
For laboratory research use only. Not for human or animal consumption.
IGF-1 LR3 at a glance
| Compound type | 83-amino-acid IGF-1 analog |
|---|---|
| Primary research target | IGF-1 receptor signaling |
| Documentation | Batch-specific Certificate of Analysis (see the COA tab) |
| Supplied for | Laboratory research use only |
Frequently asked questions
What is IGF-1 LR3?
IGF-1 LR3 is an 83-amino-acid analog of insulin-like growth factor 1 with an arginine substitution and a 13-amino-acid N-terminal extension.
What do researchers study IGF-1 LR3 for?
Reduced affinity for IGF binding proteins leaves more of the analog free to engage the IGF-1 receptor, extending its activity in vitro.
Where can I find the Certificate of Analysis?
In the COA tab on this page. Reports come from independent third-party laboratories, are tied to a specific batch, and carry a verification key that can be checked on the testing lab’s website.
Is IGF-1 LR3 for human use?
No. Karma Research Peptides supplies IGF-1 LR3 strictly for in-vitro laboratory research. It is not for human or animal consumption, and we do not provide dosing or human-use guidance.


