Quick answer: This guide groups the research compounds Karma Research Peptides supplies for metabolic signaling research (Tirzepatide, Retatrutide, Cagrilintide, MOTS-c, 5-Amino-1MQ, SLU-PP-332, NAD+) and neuro and neuroendocrine research (Semax, Selank, Cerebrolysin, Epithalon, PT-141, Kisspeptin-10). Each entry summarizes what the compound is, what it is studied for, and links to its batch-documented research material and our related articles.
Metabolic signaling research compounds
These compounds are studied for receptor pharmacology and cell signaling in metabolic pathways, including incretin and glucagon receptors, amylin receptors, AMPK and mitochondrial function. For background, see Metabolic Peptide Research: Compounds and Mechanisms.
Tirzepatide
Tirzepatide is a single-molecule dual agonist of the GIP and GLP-1 receptors. Engages both incretin receptors, with a fatty-acid side chain that extends circulating half-life through albumin binding.
Retatrutide
Retatrutide is an investigational single-molecule agonist of the GLP-1, GIP, and glucagon receptors. Engages three metabolic hormone receptors at once, allowing study of combined incretin and glucagon-pathway signaling.
Cagrilintide
Cagrilintide is a long-acting, acylated analog of the pancreatic hormone amylin. Acts at amylin receptor complexes and calcitonin receptors; its fatty-acid modification extends circulating half-life relative to native amylin.
- Cagrilintide research material (with batch COA)
- Cagrilintide in Research: A Literature Overview
- Cagrilintide HPLC Purity Testing Explained
MOTS-c
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial genome. Studied for activation of AMPK signaling and interaction with the folate cycle, linking mitochondrial and nuclear communication.
- MOTS-c research material (with batch COA)
- MOTS-c Peptide: Mechanism, Research Findings and Lab Use
- MOTS-c: An Overview of Current Research Literature
5-Amino-1MQ
5-Amino-1MQ is a small-molecule quinolinium compound studied as an inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Binds NNMT and limits the methylation of nicotinamide, which researchers use to study effects on NAD+ salvage flux and cellular methyl-donor balance.
SLU-PP-332
SLU-PP-332 is a small-molecule agonist of the estrogen-related receptors (ERRs), with the highest activity at ERRα. Activates ERR-driven transcription of genes involved in mitochondrial biogenesis and oxidative metabolism.
NAD+
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to cellular redox reactions. Serves as an electron carrier and as a substrate for sirtuins, PARPs, and CD38, linking energy metabolism with DNA repair signaling.
Neuro and neuroendocrine research peptides
These peptides are studied for neurotrophic factor expression, neurotransmitter signaling, melanocortin and kisspeptin receptor activity, and cellular aging pathways. For background, see Neuropeptides in Research: Categories and Applications.
Semax
Semax is a synthetic heptapeptide analog of the ACTH(4-10) fragment with a stabilizing Pro-Gly-Pro extension. Studied for influence on neurotrophic factor expression, including BDNF and NGF, and on dopaminergic signaling.
Selank
Selank is a synthetic heptapeptide analog of the immunomodulatory peptide tuftsin. Studied for effects on GABAergic and monoaminergic signaling and on BDNF expression in preclinical models.
Cerebrolysin
Cerebrolysin is a mixture of low-molecular-weight peptides and amino acids derived from purified porcine brain protein. Studied for composite activity resembling neurotrophic factors, with research focused on neuronal survival and synaptic signaling.
Epithalon
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on a peptide extract of the pineal gland. Studied for its proposed influence on telomerase expression and pineal signaling; published data remain largely preclinical.
PT-141
PT-141 is a cyclic heptapeptide melanocortin receptor agonist. Binds melanocortin receptors, primarily MC3R and MC4R, and is studied for the central signaling pathways those receptors activate.
Kisspeptin-10
Kisspeptin-10 is the biologically active C-terminal decapeptide of kisspeptin. Activates the KISS1 receptor (GPR54) upstream of GnRH release in the hypothalamic-pituitary axis.
- Kisspeptin-10 research material (with batch COA)
- Hormonal Signaling Peptides in Research: An Overview
Quality documentation
Every compound listed here is supplied with a batch-specific Certificate of Analysis from an independent laboratory, posted in the COA tab of its product page. To learn how to read one, see How to Verify Peptide Purity Before Research, HPLC Versus Mass Spectrometry Testing Explained and our Quality & COA Standards. For handling, see Peptide Storage and Stability: Lab Best Practices.
Research use only. All materials are sold strictly for in-vitro laboratory research. They are not for human or animal consumption, and Karma Research Peptides does not provide dosing or human-use guidance.